Description

[Bis(Trifluoroacetoxy)Iodo]Pentafluorobenzene is a specialized hypervalent iodine reagent, a key building block in advanced organic synthesis. This compound matters for its unique ability to act as a powerful and selective electrophilic fluorinating and functionalizing agent. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex fluorinated molecules.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for the late-stage introduction of fluorine atoms or trifluoroacetoxy groups into active pharmaceutical ingredients (APIs), enhancing metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of novel fluorinated pesticides and herbicides, where fluorine substitution can improve activity and environmental persistence.
• Material Science: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials that require precise fluorination.
• Organic Methodology Development: Serves as a versatile tool in academic and industrial R&D for discovering new C–F and C–O bond-forming reactions.
• Radiotracer Precursor: Potential use in the synthesis of 18F-labeled compounds for Positron Emission Tomography (PET) imaging agent development.

Basic Information

Product Name	[Bis(Trifluoroacetoxy)Iodo]Pentafluorobenzene
CAS No.	14353-88-9
Molecular Formula	C10HF11IO4
Molecular Weight	524.00 g/mol
Synonyms	Pentafluorophenyliodosyl Bis(trifluoroacetate); (Pentafluorophenyl)iodonium Bis(trifluoroacetate); Bis(trifluoroacetoxy)(pentafluorophenyl)iodine; PFPI; Pentafluorophenyl-λ3-iodanediylium Bis(trifluoroacetate); Hypervalent Iodine Reagent (PFPI); 1-(Pentafluorophenyl)-1λ3-iodanebis(trifluoroacetate)
EINECS	Contact for details

Quality Control

Our [Bis(Trifluoroacetoxy)Iodo]Pentafluorobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by NMR (1H, 19F) and HPLC analysis to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as a strong acid/organic solvent, keep away from incompatible materials such as strong reducing agents and bases. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms
19F NMR	Conforms
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.