Description

Methyl 4-Iodobutyrate is a versatile organic iodide ester, a valuable building block in synthetic organic chemistry. Its primary value lies in its reactivity, where the iodine atom serves as an excellent leaving group for nucleophilic substitution reactions, and the ester group can be further transformed. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, enabling the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing butyric acid derivatives and side chains.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in alkylation reactions, cross-coupling reactions (e.g., with palladium catalysts), and as a precursor for other functionalized butyrate compounds.
• Material Science Research: Serves as a monomer or modifying agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Can be utilized as a labeling reagent or a precursor for bioconjugation agents due to the reactive iodine handle.
• Flavor & Fragrance Industry: Potential intermediate in the synthesis of specific ester-based aroma compounds.

Basic Information

Item	Detail
Product Name	Methyl 4-Iodobutyrate
CAS No.	14273-85-9
Molecular Formula	C5H9IO2
Molecular Weight	228.03 g/mol
Synonyms	4-Iodobutanoic Acid Methyl Ester; Methyl 4-Iodobutanoate; γ-Iodobutyric Acid Methyl Ester; Methyl γ-Iodobutyrate; Butanoic acid, 4-iodo-, methyl ester; Methyl ester of 4-iodobutyric acid
EINECS	Contact for details

Quality Control

Our Methyl 4-Iodobutyrate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment ensures batch-to-batch consistency, meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise light-protected.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.495 - 1.505
Density (g/mL, 20°C)	1.70 - 1.80

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.