Description

(4-Methoxy-Phenyl)-Oxo-Acetonitrile is a versatile aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a methoxy-substituted phenyl ring and a reactive oxo-acetonitrile moiety, makes it a valuable precursor for constructing complex heterocycles and pharmaceutical intermediates. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with methoxy-phenyl pharmacophores.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and advanced organic materials.
• Heterocyclic Chemistry: Essential starting material for the construction of pyrimidines, pyrazoles, and other nitrogen-containing heterocycles.
• Research & Development: Serves as a standard reagent in academic and industrial R&D labs for method development and exploratory synthesis.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands for metal-catalyzed coupling reactions.

Basic Information

Product Name	(4-Methoxy-Phenyl)-Oxo-Acetonitrile
CAS No.	14271-83-1
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	4-Methoxyphenylglyoxylonitrile; 2-Oxo-2-(4-methoxyphenyl)acetonitrile; (4-Methoxyphenyl)(oxo)acetonitrile; p-Methoxyphenylglyoxylonitrile; 4-Methoxybenzoyl cyanide; Glyoxylonitrile, 4-methoxyphenyl-; NSC 403119; 2-(4-Methoxyphenyl)-2-oxoacetonitrile
EINECS	Contact for details

Quality Control

Our (4-Methoxy-Phenyl)-Oxo-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.