Description

4-Methylbenzoyl Cyanide is a versatile aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, featuring both a ketone and a nitrile group, which allows for the construction of complex heterocyclic and pharmaceutical intermediates. This high-purity intermediate is essential for research and development chemists and production units in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable synthesis pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyrazole, isoxazole, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where its structure contributes to the core scaffold of bioactive molecules.
• Fine Chemical Production: Serves as a starting material for dyes, pigments, and photoinitiators due to its aromatic and reactive functional groups.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.
• Ligand and Catalyst Preparation: Utilized in the development of specialized ligands for metal-catalyzed reactions and organocatalysts.

Basic Information

Product Name	4-Methylbenzoyl Cyanide
CAS No.	14271-73-9
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	p-Toluoyl cyanide; 4-Methylbenzoyl cyanide; (4-Methylphenyl)(oxo)acetonitrile; 4-Methyl-α-oxobenzeneacetonitrile; p-Methylbenzoyl cyanide; α-Oxo-4-tolueneacetonitrile; 2-Oxo-2-(p-tolyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 4-Methylbenzoyl Cyanide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	82 - 86 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.