Description

1-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinoline-4-Carboxylic Acid is a versatile heterocyclic carboxylic acid derivative that serves as a critical pharmaceutical intermediate and organic building block. Its unique fused quinoline structure makes it valuable for synthesizing complex molecules with potential biological activity. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in constructing complex heterocyclic frameworks for medicinal chemistry and material science research.
• Agrochemical Research: Intermediate for developing new generation pesticides and herbicides with specific mode-of-action.
• Dye and Pigment Synthesis: Serves as a starting material for creating specialized quinoline-based colorants.
• Ligand and Catalyst Development: Utilized in preparing chelating agents and organocatalysts for asymmetric synthesis.
• Academic and Contract Research: Essential reagent for universities and CROs conducting studies in organic chemistry and pharmacology.

Basic Information

Product Name	1-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinoline-4-Carboxylic Acid
CAS No.	14271-45-5
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	4-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-1-methyl-2-oxo-; 1-Methyl-2-oxo-1,2,3,4-tetrahydro-4-quinolinecarboxylic acid; 1-Methyl-2-oxotetrahydro-4-quinolinecarboxylic acid; 4-Carboxy-1-methyl-3,4-dihydro-2(1H)-quinolinone; 1-Methyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid; Tetrahydroquinoline carboxylic acid derivative; Keto-tetrahydroquinoline carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinoline-4-Carboxylic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.