Description

n-Cyanoacetylpyrrolidine is a versatile cyanoacetyl derivative and a key building block in organic synthesis. Its reactive cyano and carbonyl groups make it an essential intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those containing pyrrolidine and piperidine motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create diverse bioactive molecules.
• Fine Chemical Building Block: Employed in the production of specialty chemicals, dyes, and functional polymers requiring specific cyanoacetylated structures.
• Heterocyclic Chemistry: Serves as a key reactant for constructing complex nitrogen-containing heterocycles through cyclization and condensation reactions.
• Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and enzyme inhibitors due to its amide-like functionality.

Basic Information

Product Name	n-Cyanoacetylpyrrolidine
CAS No.	14227-95-3
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	2-Cyano-1-pyrrolidin-1-ylethanone; 1-(2-Cyanoacetyl)pyrrolidine; 2-Cyano-N-pyrrolidinylacetamide; Cyanoacetylpyrrolidine; Pyrrolidine, 1-(cyanoacetyl)-; NSC 163045; 2-Cyano-1-(pyrrolidin-1-yl)ethanone
EINECS	Contact for details

Quality Control

Our n-Cyanoacetylpyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, IR for identification, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.