Description

3-Cyanomethyl-Isothiazole is a versatile heterocyclic building block and key synthetic intermediate of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both an isothiazole ring and a reactive cyanomethyl group, makes it a critical precursor for the development of complex molecules. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of new-generation fungicides, herbicides, and insecticides with targeted modes of action.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic processes.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex heterocyclic frameworks.

Basic Information

Product Name	3-Cyanomethyl-Isothiazole
CAS No.	14217-70-0
Molecular Formula	C5H4N2S
Molecular Weight	124.16 g/mol
Synonyms	Isothiazole-3-acetonitrile; 3-(Cyanomethyl)-1,2-thiazole; 1,2-Thiazole-3-acetonitrile; 3-(2-Isothiazolyl)propanenitrile; 3-Isothiazoleacetonitrile; (1,2-Thiazol-3-yl)acetonitrile; 3-Cyanomethylisothiazole
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for our 3-Cyanomethyl-Isothiazole. Production follows strict internal specifications, and each lot is analyzed using advanced techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.