Description

(1R,2R)-(+)-1-Phenylpropylene Oxide is a high-value chiral epoxide building block of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a critical intermediate for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in their synthetic pathways.

Application

• As a key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• Intermediate for the production of enantiomerically pure β-blockers and other cardiovascular drugs.
• Building block for chiral ligands and catalysts used in homogeneous catalysis.
• Precursor in the synthesis of agrochemicals with specific stereochemical requirements.
• Starting material for advanced polymer research and specialty materials.
• Use in academic and industrial R&D for developing novel synthetic methodologies.

Basic Information

Product Name	(1R,2R)-(+)-1-Phenylpropylene Oxide
CAS No.	14212-54-5
Molecular Formula	C9H10O
Molecular Weight	134.18 g/mol
Synonyms	(+)-(1R,2R)-1-Phenylpropylene Oxide; (1R,2R)-(+)-1-Phenyl-1,2-epoxypropane; (R,R)-(+)-1-Phenylpropylene Oxide; (1R,2R)-1-Phenylpropylene Oxide; (1R,2R)-1-Phenyl-1,2-epoxypropane; trans-(+)-1-Phenylpropylene Oxide; (R,R)-1-Phenylpropylene Oxide; (+)-trans-1-Phenylpropylene Oxide
EINECS	Contact for details

Quality Control

Our (1R,2R)-(+)-1-Phenylpropylene Oxide is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination and identity confirmation by spectroscopic methods. Certificates of Analysis (COA) detailing purity, specific rotation, and impurity profiles are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.