Description

Bis(p-Toluenesulfonyl)Diazomethane is a versatile and highly reactive diazo transfer reagent, widely recognized for its utility in organic synthesis. Its core value lies in its ability to efficiently introduce diazo functional groups into target molecules, enabling key transformations such as cyclopropanation and homologation. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and high-purity building blocks for complex molecule construction.

Application

• Diazo Transfer Reagent: Primary use for the efficient transfer of diazo groups to active methylene compounds, carboxylic acids, and other nucleophiles.
• Pharmaceutical Intermediate Synthesis: Key building block in the synthesis of complex heterocycles and strained ring systems like cyclopropanes, which are prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel pesticides and herbicides through the creation of specialized carbon frameworks.
• Polymer & Material Science: Employed in the synthesis of specialty polymers and functional materials that require precise molecular architecture.
• Catalyst & Ligand Development: Serves as a precursor for generating metal carbene complexes used in catalytic cycles.
• Academic & Process Chemistry: A staple reagent in research laboratories for methodology development and scalable process optimization.

Basic Information

Product Name	Bis(p-Toluenesulfonyl)Diazomethane
CAS No.	14159-45-6
Molecular Formula	C15H14N2O4S2
Molecular Weight	350.41 g/mol
Synonyms	Bis(4-methylbenzenesulfonyl)diazomethane; Di-p-toluenesulfonyldiazomethane; p-Toluenesulfonyldiazomethane, bis-; Diazo-bis-p-tolylsulfone; DTDM; Bis(tosyl)diazomethane; (Diazomethylene)bis(4-methylbenzenesulfone); 1,1'-(Diazomethylene)bis(4-methylbenzene)sulfone
EINECS	Contact for details

Quality Control

Our Bis(p-Toluenesulfonyl)Diazomethane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature (store under inert atmosphere), it is recommended to handle under an inert atmosphere such as nitrogen or argon and minimize exposure to air and moisture during use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.