Description

2-Methyl-1,1-Cyclobutanedicarboxylic Acid Dimethyl Ester is a high-purity, functionalized cyclobutane derivative that serves as a versatile and valuable synthetic intermediate. Its unique strained-ring structure and ester functionalities make it a critical building block for the development of complex organic molecules. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring constrained, bicyclic, or spirocyclic frameworks to modulate biological activity and pharmacokinetic properties.
• Agrochemical Synthesis: Serves as a key precursor for creating new generations of herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Advanced Material Monomer: Employed in the research and development of specialty polymers, coatings, and resins where the cyclobutane ring can impart unique thermal and mechanical properties.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex natural product analogs and exploring new chemical spaces in drug discovery.
• Ligand and Catalyst Development: Acts as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Potential intermediate for the synthesis of musky or woody odorants due to its polycyclic nature.

Basic Information

Product Name	2-Methyl-1,1-Cyclobutanedicarboxylic Acid Dimethyl Ester
CAS No.	14132-43-5
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	Dimethyl 2-Methyl-1,1-cyclobutanedicarboxylate; 1,1-Cyclobutanedicarboxylic Acid, 2-Methyl-, Dimethyl Ester; Methyl 2-Methyl-1,1-cyclobutanedicarboxylate; 2-Methyl-1,1-cyclobutanedicarboxylic acid methyl ester; Cyclobutanedicarboxylic Acid Dimethyl Ester Derivative
EINECS	Contact for details

Quality Control

Our 2-Methyl-1,1-Cyclobutanedicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance for sensitive synthetic applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.