Description

Ethyl 4-(Methylthio)-3-Oxobutanoate is a versatile sulfur-containing β-keto ester derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a ketone and an ester group adjacent to a methylthio moiety, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable and scalable synthons.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether or heterocyclic structures.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that require specific sulfur-based functional groups.
• Flavor & Fragrance Industry: Used in the controlled synthesis of sulfur-containing flavor compounds, contributing to meaty, roasted, or tropical notes.
• Organic Synthesis Reagent: Employed in Michael additions, Claisen condensations, and cyclization reactions to create complex molecular architectures.
• Material Science Research: Monomer or precursor for synthesizing specialized polymers and functional materials with tailored properties.

Basic Information

Product Name	Ethyl 4-(Methylthio)-3-Oxobutanoate
CAS No.	14109-74-1
Molecular Formula	C7H12O3S
Molecular Weight	176.23 g/mol
Synonyms	Ethyl 4-(Methylthio)-3-oxobutanoate; Ethyl 4-Methylthio-3-oxobutanoate; 4-(Methylthio)-3-oxobutanoic Acid Ethyl Ester; 3-Oxo-4-(methylthio)butyric Acid Ethyl Ester; Ethyl 3-Oxo-4-(methylthio)butyrate; Ethyl 4-(Methylmercapto)-3-oxobutyrate; Ethyl 3-Oxo-4-(methylmercapto)butyrate; Ethyl 4-(Methylsulfanyl)-3-oxobutanoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(Methylthio)-3-Oxobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.480 - 1.490
Density (20°C)	1.150 - 1.170 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.