Description

((4-Bromo-2-Methyl-5-Oxo-1-Phenyl(3-Pyrazolin-3-Yl))Methyl)Thiocarboxamidine, Hydrobromide is a high-purity, specialized heterocyclic organic compound primarily used as a critical building block in advanced chemical synthesis. This compound is valued for its unique molecular structure, which incorporates a pyrazolinone core functionalized with bromine and thiocarboxamidine groups, making it a versatile intermediate for pharmaceutical and agrochemical research. It is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition or protein-ligand interactions due to its potential reactive sites.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialized polymers with unique electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	((4-Bromo-2-Methyl-5-Oxo-1-Phenyl(3-Pyrazolin-3-Yl))Methyl)Thiocarboxamidine, Hydrobromide
CAS No.	14039-66-8
Molecular Formula	C12H12BrN5OS • HBr
Molecular Weight	424.09 g/mol
Synonyms	4-Bromo-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carbothioamide hydrobromide; 3-[(Aminoiminomethyl)thio]methyl]-4-bromo-2-methyl-5-oxo-1-phenyl-3-pyrazoline hydrobromide; Thiocarboxamidine, [(4-bromo-2-methyl-5-oxo-1-phenyl-3-pyrazolin-3-yl)methyl]-, hydrobromide; 14039-66-8; 4-Bromo-2-methyl-1-phenyl-1,2-dihydro-3H-pyrazol-3-one 3-carbothioamide hydrobromide
EINECS	Contact for details

Quality Control

Our production of ((4-Bromo-2-Methyl-5-Oxo-1-Phenyl(3-Pyrazolin-3-Yl))Methyl)Thiocarboxamidine, Hydrobromide adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.