Description

2-Diazo-2-Nitroacetic Acid tert-Butyl Ester is a specialized diazo compound that serves as a versatile building block in advanced organic synthesis. Its unique molecular structure, featuring both a diazo and a nitro group, makes it a valuable precursor for generating reactive carbene intermediates under mild conditions. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, enabling the synthesis of complex nitrogen-containing heterocycles and novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for nitrogen-rich heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific nitration and cyclization steps.
• Polymer & Materials Science: Employed as a functional monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Carbene Chemistry: Serves as a stable and convenient source of reactive carbene species for cyclopropanation, C-H insertion, and other metal-catalyzed transformations.
• Energetic Materials Research: Investigated as a component in the design of novel high-energy-density materials (HEDMs) due to its diazo and nitro functional groups.
• Academic & R&D Laboratories: A critical reagent for methodological development in organic chemistry and the exploration of new reaction pathways.

Basic Information

Product Name	2-Diazo-2-Nitroacetic Acid tert-Butyl Ester
CAS No.	13994-40-6
Molecular Formula	C6H9N3O4
Molecular Weight	187.15 g/mol
Synonyms	tert-Butyl 2-diazo-2-nitroacetate; 2-Diazo-2-nitroacetic acid tert-butyl ester; 2-Nitro-2-diazoacetic acid 1,1-dimethylethyl ester; tert-Butyl diazonitroacetate; 1,1-Dimethylethyl 2-diazo-2-nitroacetate; 2-Diazo-2-nitro-acetic acid tert-butyl ester; (tert-Butoxycarbonyl)diazonitromethane
EINECS	Contact for details

Quality Control

Our 2-Diazo-2-Nitroacetic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C/59-77°F). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.