Description

2,4-Difluorobenzenesulfonyl Chloride is a key fluorinated aromatic sulfonyl chloride derivative, serving as a versatile and high-value building block in advanced organic synthesis. Its primary value lies in its dual reactive sites, enabling the efficient introduction of the 2,4-difluorophenylsulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms for improved bioactivity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, such as sulfonated polymers for ion-exchange membranes.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of fluorinated dyes and pigments, offering superior lightfastness and chemical resistance.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and process R&D for constructing complex molecular architectures via sulfonamide and sulfonate ester formation.

Basic Information

Product Name	2,4-Difluorobenzenesulfonyl Chloride
CAS No.	13918-92-8
Molecular Formula	C6H3ClF2O2S
Molecular Weight	212.60 g/mol
Synonyms	2,4-Difluorobenzene-1-sulfonyl chloride; 1,3-Difluoro-4-sulfonylchloridobenzene; Benzenesulfonyl chloride, 2,4-difluoro-; 2,4-DFBS-Cl; 2,4-Difluorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,4-Difluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water; ensure containers are kept tightly sealed in a dry environment. Keep away from strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.