Description

3-Hydroxyglutaronitrile is a versatile bifunctional chemical intermediate featuring both nitrile and hydroxyl groups. This unique structure makes it a valuable building block for the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical industries. Key applications include its use as a precursor for statin drugs and other active pharmaceutical ingredients (APIs).

Application

• Key intermediate in the synthesis of statin-class pharmaceuticals (e.g., Atorvastatin, Rosuvastatin).
• Building block for the production of chiral compounds and other fine chemicals.
• Precursor in the manufacture of specialty polymers and functional materials.
• Intermediate for agrochemicals and other biologically active compounds.
• Used in research and development for novel pharmaceutical candidates and chemical entities.
• Starting material for the synthesis of lactones and other cyclic structures.

Basic Information

Product Name	3-Hydroxyglutaronitrile
CAS No.	13880-89-2
Molecular Formula	C5H6N2O
Molecular Weight	110.11 g/mol
Synonyms	3-Hydroxypentanedinitrile; 1,3-Dicyano-2-propanol; 2-Propanol, 1,3-dicyano-; 3-Hydroxy-1,5-dicyanopentane; Glutaronitrile, 3-hydroxy-; 3-HGN
EINECS	237-642-6

Quality Control

Our 3-Hydroxyglutaronitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. This product is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.