Description

1-Adamantanamine,Hydrochloride.(L-)- (8Ci) is a high-purity, chiral derivative of adamantane, a structurally unique and rigid hydrocarbon framework. This compound is valued for its role as a versatile chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by research institutions and chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials that leverage the adamantane scaffold's stability and three-dimensional geometry.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of antiviral agents, neurological drugs, and other therapeutic compounds.
• Asymmetric Synthesis: Employed as a chiral amine source or auxiliary in catalytic reactions to induce stereoselectivity.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the adamantane structure confers metabolic stability.
• Material Science: Serves as a building block for advanced polymers, dendrimers, and supramolecular structures with tailored properties.
• Chemical Biology & Proteomics: Utilized as a molecular probe or tag due to its bulky, hydrophobic character.
• Catalyst Ligand Development: The chiral amine can be incorporated into ligands for metal-catalyzed reactions.

Basic Information

Product Name	1-Adamantanamine,Hydrochloride.(L)- (8Ci)
CAS No.	13878-11-0
Molecular Formula	C10H18ClN
Molecular Weight	187.71 g/mol
Synonyms	(1S)-1-Adamantanamine Hydrochloride; L-1-Aminoadamantane Hydrochloride; (‑)-1-Adamantylamine Hydrochloride; (1S)-Adamantan-1-amine Hydrochloride; (S)-1-Adamantanamine HCl; (‑)-Adamantan-1-amine Hydrochloride; UNII-9K8C6W6FQM; Amantadine Impurity C (L- enantiomer hydrochloride)
EINECS	Contact for details

Quality Control

Our 1-Adamantanamine,Hydrochloride.(L)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (L-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.