Description

(1R,5S)-6,6-Dimethylbicyclo[3.1.0]Hexan-3-One (Wx625149) is a high-purity, chiral bicyclic ketone that serves as a critical building block in advanced organic synthesis. Its unique, rigid molecular framework makes it an invaluable intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including potential antiviral, anti-inflammatory, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its bicyclic structure can contribute to unique biological activity.
• Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing specific terpenoid-derived aroma molecules, contributing to complex scent profiles.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with tailored thermal or mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development and optimization of new chiral catalysts.
• Academic & R&D Laboratories: Used in methodological studies and total synthesis projects to explore new chemical transformations and build molecular complexity.

Basic Information

Product Name	(1R,5S)-6,6-Dimethylbicyclo[3.1.0]Hexan-3-One (Wx625149)
CAS No.	13855-29-3
Molecular Formula	C8H12O
Molecular Weight	124.18 g/mol
Synonyms	(1R,5S)-6,6-Dimethylbicyclo[3.1.0]hexan-3-one; (1R,5S)-3-Thujone; (-)-3-Thujone; (1R,5S)-3-Isothujone; Bicyclo[3.1.0]hexan-3-one, 6,6-dimethyl-, (1R,5S)-; Wx625149
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Every batch of (1R,5S)-6,6-Dimethylbicyclo[3.1.0]Hexan-3-One is analyzed to ensure high chemical and enantiomeric purity, typically meeting standards suitable for research and cGMP starting material applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), chiral purity, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.