Description

Benzyl 4-Nitrophenyl Carbonate is a versatile and highly reactive chemical intermediate primarily used in organic synthesis. This compound is valued for its role as a protective group reagent and an efficient coupling agent in the formation of carbonates and carbamates. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for carbonate-linked prodrugs and polymer conjugates.
• Peptide & Oligonucleotide Synthesis: Acts as a reagent for the introduction of the benzyloxycarbonyl (Cbz) protecting group or as a coupling agent in solid-phase synthesis.
• Polymer Chemistry: Used in the preparation of functional polymers, polycarbonates, and polymeric materials with tailored properties.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Bioconjugation: Facilitates the covalent attachment of molecules (e.g., drugs, dyes) to proteins, antibodies, or other biomolecules for diagnostic and therapeutic applications.
• Material Science Research: Employed in surface modification and the creation of novel organic-inorganic hybrid materials.

Basic Information

Product Name	Benzyl 4-Nitrophenyl Carbonate
CAS No.	13795-24-9
Molecular Formula	C14H11NO5
Molecular Weight	273.24 g/mol
Synonyms	4-Nitrophenyl Benzyl Carbonate; Benzyl (4-Nitrophenyl) Carbonate; Benzyl p-Nitrophenyl Carbonate; p-Nitrophenyl Benzyl Carbonate; Carbonochloridic Acid, 4-Nitrophenyl Ester, Benzyl Ester; Benzyloxycarbonyl 4-Nitrophenyl Carbonate; Cbz-ONp; Z-ONp
EINECS	Contact for details

Quality Control

Our Benzyl 4-Nitrophenyl Carbonate is produced and handled under strict quality management protocols. We offer material suitable for research and industrial synthesis, with typical purity grades exceeding 97%. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and other analytical techniques. Specifications can be tailored to meet specific project requirements, including cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.