Description

[3R-(3Alpha,3Abeta,6Alpha,7Beta,8Aalpha)]-Hexahydro-3,6,8,8-Tetramethyl-1H-3A,7-Methanoazulen-5(4H)-One is a high-purity, complex sesquiterpenoid ketone with a distinctive fused ring structure. This compound matters as a versatile and valuable intermediate and building block for advanced organic synthesis, particularly in the fragrance and pharmaceutical sectors. It is primarily needed by R&D chemists and manufacturers in the flavor & fragrance, fine chemical, and life science industries for creating novel compounds and specialty ingredients. Its unique stereochemistry and functional group make it a key starting material for complex molecular architectures.

Application

• Fragrance & Flavor Intermediate: Serves as a crucial precursor in the synthesis of high-value amber, woody, and musk odorants for perfumery and flavoring agents.
• Pharmaceutical Research: Acts as a sophisticated chiral building block for the development of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Fine Chemical Synthesis: Used in organic chemistry research and production for constructing complex natural product analogs and specialty chemicals.
• Aroma Chemical Production: A key starting material in the manufacture of proprietary aroma molecules with specific olfactory profiles.
• Academic & Industrial R&D: Employed in methodological studies and as a reference standard in stereochemistry and synthetic route development.

Basic Information

Product Name	[3R-(3Alpha,3Abeta,6Alpha,7Beta,8Aalpha)]-Hexahydro-3,6,8,8-Tetramethyl-1H-3A,7-Methanoazulen-5(4H)-One
CAS No.	13794-73-5
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	Ambrox; Ambroxan; Ambroxide; (3aR,5aS,9aS,9bR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan; (-)-Ambrox; d,l-Ambrox; 1,5,5,9-Tetramethyl-13-oxatricyclo[8.3.0.0(4,9)]tridecane; 3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan; Octalox
EINECS	Contact for details

Quality Control

Our [3R-(3Alpha,3Abeta,6Alpha,7Beta,8Aalpha)]-Hexahydro-3,6,8,8-Tetramethyl-1H-3A,7-Methanoazulen-5(4H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistent stereochemical integrity, and batch-to-batch reliability. Certificates of Analysis (COA) detailing identity, purity (by GC/HPLC), and specific rotation are available upon request. We adhere to cGMP principles where applicable to meet the stringent demands of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Assay (GC/HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.