Description

2,2,3-Trimethyl-1,1-Cyclopropanedicarbonitrile is a specialized, high-purity cyclopropane derivative characterized by its unique sterically hindered structure and the presence of two nitrile functional groups. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in fine organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce complex, rigid molecular frameworks into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a rigid, three-membered carbocyclic core.
• Agrochemical Synthesis: Used as a building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with unique thermal and mechanical properties.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and other functional materials.
• Organic Synthesis Reagent: Utilized in cycloaddition reactions and as a source of the nitrile group for further functionalization into amides, acids, or amines.

Basic Information

Product Name	2,2,3-Trimethyl-1,1-Cyclopropanedicarbonitrile
CAS No.	13764-28-8
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	1,1-Cyclopropanedicarbonitrile, 2,2,3-trimethyl-; 2,2,3-Trimethylcyclopropane-1,1-dicarbonitrile; Trimethylcyclopropanedicarbonitrile; NSC 163022; Cyclopropane-1,1-dicarbonitrile, 2,2,3-trimethyl-
EINECS	Contact for details

Quality Control

Our 2,2,3-Trimethyl-1,1-Cyclopropanedicarbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.