Description

Benzeneacetic Acid, 2-(Bromomethyl)- is a versatile brominated aromatic building block of significant synthetic utility. Its core value lies in its bifunctional reactivity, featuring both a carboxylic acid and a reactive bromomethyl group, enabling its use in the construction of complex molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates. The product is supplied under the CAS registry number 13737-35-4.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those requiring phenethylamine or arylacetic acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the bromomethyl group facilitates further alkylation or coupling reactions.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and advanced materials requiring specific aromatic acid functionalities.
• Peptidomimetic Research: Useful in medicinal chemistry for the design and synthesis of peptide analogs and enzyme inhibitors.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, after appropriate derivatization.

Basic Information

Product Name	Benzeneacetic Acid, 2-(Bromomethyl)-
CAS No.	13737-35-4
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	2-(Bromomethyl)phenylacetic Acid; (2-Bromomethyl)phenylacetic Acid; α-(Bromomethyl)benzeneacetic Acid; o-(Bromomethyl)phenylacetic Acid; 2-Bromomethylbenzeneacetic Acid; (o-Bromomethyl)phenylacetic Acid; Bromomethylphenylacetic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay and impurity profiles are available upon request. We adhere to strict in-house specifications to meet the demanding requirements of research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.