Description

(4-Chloro-3-Methoxyphenyl)Acetonitrile is a versatile aromatic nitrile building block with a chlorinated methoxyphenyl core, offering a reactive cyano group for further chemical transformations. This compound is crucial for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate. It is primarily sought by research and development chemists and process engineers in fine chemical manufacturing for creating active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those with chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactive nitrile group for constructing heterocyclic compounds.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced organic electronic materials due to its aromatic structure and potential for functionalization.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and organic pigments.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecules via reactions such as hydrolysis, reduction, and cyclization.
• Cross-Coupling Reactions: A potential substrate for palladium-catalyzed coupling reactions (e.g., Suzuki, Heck) to create biaryl structures.

Basic Information

Product Name	(4-Chloro-3-Methoxyphenyl)Acetonitrile
CAS No.	13726-21-1
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	2-(4-Chloro-3-methoxyphenyl)acetonitrile; (4-Chloro-3-methoxyphenyl)ethanenitrile; 4-Chloro-3-methoxybenzyl cyanide; 1-Chloro-2-methoxy-4-(cyanomethyl)benzene; 4-Chloro-m-anisylacetonitrile; 3-Methoxy-4-chlorophenylacetonitrile; p-Chloro-m-methoxyphenylacetonitrile
EINECS	Contact for details

Quality Control

Our (4-Chloro-3-Methoxyphenyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.