Description

3-Amino-1-Benzyl-Piperidine-3-Carboxylic Acid is a high-value, multifunctional piperidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both amino and carboxylic acid functional groups on the same carbon atom, makes it indispensable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and therapeutic agent research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of central nervous system (CNS) targeting drugs, receptor modulators, and other bioactive molecules.
• Organic Synthesis Building Block: Used in asymmetric synthesis, peptidomimetics, and the construction of complex heterocyclic compounds due to its constrained piperidine ring and bifunctional nature.
• Ligand and Catalyst Precursor: Employed in the development of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as an intermediate in the synthesis of advanced, targeted crop protection agents.
• Academic and R&D Laboratories: Utilized in medicinal chemistry programs and for studying structure-activity relationships (SAR).

Basic Information

Product Name	3-Amino-1-Benzyl-Piperidine-3-Carboxylic Acid
CAS No.	13725-02-5
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	1-Benzyl-3-aminopiperidine-3-carboxylic acid; 3-Amino-1-benzyl-3-piperidinecarboxylic acid; 3-Amino-1-benzylpiperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 3-amino-1-(phenylmethyl)-; NSC 163045; 1-Benzyl-3-amino-3-piperidinecarboxylic acid; (±)-3-Amino-1-benzylpiperidine-3-carboxylic acid; 3-Amino-1-(phenylmethyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-1-Benzyl-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and chiral purity analysis. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.