Description

2,2-Dibromo-1-p-tolylethanone is a specialized brominated aromatic ketone of significant interest in advanced organic synthesis. This compound serves as a versatile and highly reactive building block, enabling the introduction of key functional groups into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring dibromoacetyl or related functional groups.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its reactive bromine atoms facilitate further chemical modifications.
• Fine Chemical Building Block: Employed in the preparation of specialty chemicals, dyes, and pigments due to its aromatic ketone structure.
• Cross-Coupling Reactions: Serves as a substrate in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form carbon-carbon bonds.
• Heterocyclic Chemistry: A valuable starting material for the construction of nitrogen- and oxygen-containing heterocycles, which are common scaffolds in medicinal chemistry.
• Polymer Chemistry Research: Investigated as a monomer or functionalization agent for creating polymers with specific bromine-based reactivity or properties.

Basic Information

Product Name	2,2-Dibromo-1-p-Tolylethanone
CAS No.	13664-98-7
Molecular Formula	C9H8Br2O
Molecular Weight	291.97 g/mol
Synonyms	2,2-Dibromo-1-(4-methylphenyl)ethanone; p-Methylphenacyl Bromide, Dibromo; 1-(4-Methylphenyl)-2,2-dibromoethanone; 4-Methylphenacyl Bromide, Dibromo; α,α-Dibromo-4-methylacetophenone; Dibromo-p-tolyl ethanone; 2,2-Dibromo-1-(p-tolyl)ethanone; 4'-Methyl-2,2-dibromoacetophenone
EINECS	Contact for details

Quality Control

Our 2,2-Dibromo-1-p-tolylethanone is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	74 - 78 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.