Description

17-Hydroxy-16Beta-Methyl-5Beta-Pregn-9(11)-Ene-3,20-Dione is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the development of advanced corticosteroid and progestogen-based active pharmaceutical ingredients (APIs). It is essential for research institutions and manufacturers in the pharmaceutical industry engaged in the development and production of steroidal drugs, where precise molecular structure and high purity are paramount for efficacy and regulatory compliance.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent corticosteroid drugs.
• Steroid Hormone Research: Used as a reference standard and starting material in academic and industrial research exploring new steroidal entities.
• API Development: Critical for the process development and scale-up manufacturing of novel anti-inflammatory and hormonal therapeutic agents.
• Process Chemistry: Employed in optimizing synthetic routes for steroidal compounds to improve yield, purity, and cost-efficiency.
• GMP Manufacturing: Supplied as a qualified starting material for the production of active pharmaceutical ingredients under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	17-Hydroxy-16Beta-Methyl-5Beta-Pregn-9(11)-Ene-3,20-Dione
CAS No.	13656-78-5
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	9(11)-Dehydro-16β-methylprednisolone; 16β-Methyl-9(11)-dehydroprednisolone; 17-Hydroxy-16β-methylpregna-9(11)-ene-3,20-dione; 16β-Methyl-δ9(11)-pregnene-3,20-dione-17-ol; 16β-Methyl-9,11-dehydroprednisolone; 9,11-Dehydro-16β-methylprednisolone; 16β-Methyl-δ9(11)-corticosterone
EINECS	Contact for details

Quality Control

Our 17-Hydroxy-16Beta-Methyl-5Beta-Pregn-9(11)-Ene-3,20-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and purity, to ensure it meets stringent specifications suitable for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.