Description

4-Piperidin-1-Ylmethyl-1H-Quinolin-2-One is a high-purity organic compound with the CAS number 13629-28-2, serving as a crucial advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of potential APIs with quinolinone and piperidine pharmacophores.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard in pharmacological studies.
• Contract Synthesis: Supplied to CROs and CMOs for custom synthesis projects and scale-up activities.
• Academic Research: Employed in university and institutional labs for organic synthesis methodology development and bioorganic chemistry.

Basic Information

Product Name	4-Piperidin-1-Ylmethyl-1H-Quinolin-2-One
CAS No.	13629-28-2
Molecular Formula	C16H20N2O
Molecular Weight	256.35 g/mol
Synonyms	1H-Quinolin-2-one, 4-[(1-piperidinyl)methyl]-; 4-(Piperidin-1-ylmethyl)quinolin-2(1H)-one; 4-Piperidin-1-ylmethyl-1H-quinolin-2-one; 4-[(Piperidin-1-yl)methyl]-2(1H)-quinolinone; 2-Quinolinone, 4-(1-piperidinylmethyl)-1H-; 13629-28-2; 4-(1-Piperidinylmethyl)-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 4-Piperidin-1-Ylmethyl-1H-Quinolin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.