Description

1-Fluoro-3-(2-Nitro-Imidazol-1-Yl)-Propan-2-Ol is a specialized fluorinated nitroimidazole derivative, a key synthetic intermediate in the development of advanced pharmaceuticals and diagnostic agents. Its molecular structure, featuring both a nitroimidazole moiety and a fluorinated propanol side chain, makes it a critical building block for creating targeted bioactive compounds. This high-purity intermediate is essential for research and production in the pharmaceutical and biotechnology sectors, particularly for applications requiring precise molecular modifications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nitroimidazole-based drugs, including potential radiosensitizers and chemotherapeutic agents.
• Biomedical Research: Used in the development of hypoxia-targeting compounds and probes for studying tumor microenvironments in preclinical research.
• Diagnostic Agent Synthesis: Serves as a key starting material for creating fluorinated markers and contrast agents used in medical imaging.
• Radiopharmaceuticals: Employed in the synthesis of precursors for Positron Emission Tomography (PET) tracers, leveraging the fluorine atom for 18F labeling.
• Chemical Biology: Utilized for synthesizing molecular tools and probes to study enzyme mechanisms and biological pathways involving nitroreductases.
• Antiparasitic Drug Development: Acts as an intermediate in the research and synthesis of next-generation antiprotozoal medications.

Basic Information

Product Name	1-Fluoro-3-(2-Nitro-Imidazol-1-Yl)-Propan-2-Ol
CAS No.	13551-89-8
Molecular Formula	C6H8FN3O3
Molecular Weight	189.15 g/mol
Synonyms	1-Fluoro-3-(2-nitro-1H-imidazol-1-yl)-2-propanol; 2-Nitro-1-[3-fluoro-2-hydroxypropyl]imidazole; 3-Fluoro-1-(2-nitroimidazol-1-yl)-2-propanol; 1-(3-Fluoro-2-hydroxypropyl)-2-nitroimidazole; FNIP; Fluoronitroimidazole propanol; 2-Nitro-1-(3-fluoro-2-hydroxypropyl)-1H-imidazole
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-(2-Nitro-Imidazol-1-Yl)-Propan-2-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.