Description

3-Bromo-2-Hydroxypyridine is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a bromine atom and a hydroxyl group on the pyridine ring, makes it a critical intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce functionalized pyridine motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with pyridine-based cores, such as kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromo-hydroxypyridine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, including charge-transport layers and light-emitting compounds.
• Chemical Biology Probes: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Bromo-2-Hydroxypyridine
CAS No.	13466-43-8
Molecular Formula	C5H4BrNO
Molecular Weight	173.99 g/mol
Synonyms	2-Hydroxy-3-bromopyridine; 3-Bromo-2-pyridinol; 3-Bromo-2(1H)-pyridinone; 3-Bromo-1H-pyridin-2-one; 3-Bromopyridin-2-ol; 3-Bromo-2-hydroxypyridine; 2-Pyridinol, 3-bromo-
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.