Description

5-(Trifluoromethyl)-2(3H)-Benzoxazolethione is a versatile heterocyclic building block characterized by its benzoxazole core and trifluoromethyl substituent. This compound is valued for its unique electronic properties and stability, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in areas targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Organic Synthesis Reagent: Acts as a versatile scaffold in medicinal chemistry for constructing complex heterocyclic systems through various coupling and cyclization reactions.
• Chemical Biology Probe: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	5-(Trifluoromethyl)-2(3H)-Benzoxazolethione
CAS No.	13451-80-4
Molecular Formula	C8H4F3NOS
Molecular Weight	219.18 g/mol
Synonyms	2(3H)-Benzoxazolethione, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-benzoxazolethiol; 5-(Trifluoromethyl)-2-mercaptobenzoxazole; 2-Mercapto-5-(trifluoromethyl)benzoxazole; 5-Trifluoromethyl-2-mercaptobenzoxazole; 2-Benzoxazolethiol, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)benzoxazole-2-thiol
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)-2(3H)-Benzoxazolethione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and meet the exacting standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.