Description

Iodomethyl Acetate CAS NO 13398-11-3 is a versatile organic iodide ester primarily used as a key reagent in organic synthesis. Its value lies in its ability to serve as an efficient methylene transfer agent and a source of iodomethyl groups for functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring iodomethyl or acetoxymethyl functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific halogenated intermediates are necessary.
• Organic Synthesis Reagent: Employed in alkylation and functionalization reactions, including the preparation of cyclopropanes and other strained ring systems.
• Material Science Research: Acts as a precursor or modifying agent in the development of novel polymers and advanced organic materials.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex molecular architectures.
• Laboratory-scale Chemical Development: A valuable tool for process chemists and research scientists in method development and scale-up studies.

Basic Information

Product Name	Iodomethyl Acetate
CAS No.	13398-11-3
Molecular Formula	C3H5IO2
Molecular Weight	199.98 g/mol
Synonyms	Acetic Acid Iodomethyl Ester; Acetoxymethyl Iodide; (Iodomethyl) Acetate; Iodomethylacetate; Iodo Methyl Acetate; Methyl Iodide Acetate; Iodomethanol Acetate; EINECS 236-485-4
EINECS	236-485-4

Quality Control

Our Iodomethyl Acetate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Gravity (20°C)	1.80 - 1.90

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.