Description

Cyclopentanol, 2-Fluoro-, trans- CAS NO 13378-44-4 is a high-purity, fluorinated cyclopentanol derivative characterized by its specific stereochemistry. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, where the introduction of fluorine can dramatically alter the biological activity and metabolic stability of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fluorine Chemistry Research: An essential standard and building block in academic and industrial laboratories studying the effects of fluorination on molecular properties.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Material Science Precursor: Potential use in the synthesis of fluorinated polymers or liquid crystals with unique electronic or optical properties.

Basic Information

Product Name	Cyclopentanol, 2-Fluoro-, trans-
CAS No.	13378-44-4
Molecular Formula	C5H9FO
Molecular Weight	104.12 g/mol
Synonyms	trans-2-Fluorocyclopentanol; (1R,2R)-2-Fluorocyclopentanol; (1S,2S)-2-Fluorocyclopentanol; 2-Fluoro-cis-cyclopentanol (common misnomer); Fluorocyclopentanol; 2-Fluorocyclopentanol, trans-; Cyclopentanol, 2-fluoro-, (1R,2R)-rel-; 2-Fluorocyclopentanol
EINECS	Contact for details

Quality Control

Our Cyclopentanol, 2-Fluoro-, trans- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under an inert atmosphere (nitrogen or argon) is recommended to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% de (trans isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.