Description

2-(3-Chloro-4-Cyclohexyl-Phenyl)Propanoic Acid CAS NO 13376-38-0 is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of advanced pharmaceutical active ingredients, where its specific stereochemistry and purity are paramount. It is primarily required by manufacturers in the pharmaceutical and fine chemical sectors for the development of next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the research and commercial production of specific API candidates targeting inflammation and pain.
• Fine Chemical Research: Valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(3-Chloro-4-Cyclohexyl-Phenyl)Propanoic Acid
CAS No.	13376-38-0
Molecular Formula	C15H19ClO2
Molecular Weight	266.76 g/mol
Synonyms	2-(3-Chloro-4-cyclohexylphenyl)propanoic acid; α-Methyl-3-chloro-4-cyclohexylbenzeneacetic acid; 3-Chloro-4-cyclohexylhydratropic acid; 2-(3-Chloro-4-cyclohexylphenyl)propionic acid; (RS)-2-(3-Chloro-4-cyclohexylphenyl)propanoic acid; (±)-2-(3-Chloro-4-cyclohexylphenyl)propanoic acid; 13376-38-0; NSC 163049
EINECS	Contact for details

Quality Control

Our 2-(3-Chloro-4-Cyclohexyl-Phenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Individual Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.