Description

1-(3-Fluoro-4-Methanesulfonylphenyl)Ethan-1-One is a high-purity, fluorinated aromatic ketone derivative featuring a methanesulfonyl substituent, making it a valuable and versatile synthetic intermediate. This compound is critical for advanced organic synthesis, particularly in constructing complex molecular architectures for active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for its role in introducing key functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and polar sulfone group.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-(3-Fluoro-4-Methanesulfonylphenyl)Ethan-1-One
CAS No.	13372-52-6
Molecular Formula	C9H9FO3S
Molecular Weight	216.23 g/mol
Synonyms	3'-Fluoro-4'-(methylsulfonyl)acetophenone; 1-Acetyl-3-fluoro-4-(methylsulfonyl)benzene; 3-Fluoro-4-methylsulfonylacetophenone; 4-Acetyl-2-fluoro-1-(methylsulfonyl)benzene; 1-(3-Fluoro-4-(methylsulfonyl)phenyl)ethanone; Ethanone, 1-[3-fluoro-4-(methylsulfonyl)phenyl]-; 3-Fluoro-4-methanesulfonyl acetophenone
EINECS	Contact for details

Quality Control

Our production of 1-(3-Fluoro-4-Methanesulfonylphenyl)Ethan-1-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and reliability for our global B2B partners in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.