Description

2-Piperazin-1-Yl-Phenylamine is a versatile aromatic amine derivative featuring a piperazine substituent, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of high-value, complex molecules, particularly within the pharmaceutical sector. Industries that need it include pharmaceutical R&D for active pharmaceutical ingredient (API) synthesis, agrochemical manufacturing for novel crop protection agents, and specialty chemical producers developing dyes, pigments, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and cardiovascular diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its aromatic amine core for bioactive molecule construction.
• Dye and Pigment Manufacturing: Serves as a key intermediate for producing azo dyes and other complex colorants for industrial and textile applications.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and epoxy hardeners.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities (NCEs).
• Ligand Synthesis for Catalysis: Used to create complex ligands for transition metal catalysts used in asymmetric synthesis and other advanced reactions.

Basic Information

Product Name	2-Piperazin-1-Yl-Phenylamine
CAS No.	13339-02-1
Molecular Formula	C10H15N3
Molecular Weight	177.25 g/mol
Synonyms	1-(2-Aminophenyl)piperazine; N-(2-Aminophenyl)piperazine; 2-(Piperazin-1-yl)aniline; 2-Aminophenylpiperazine; o-Aminophenylpiperazine; 1-Piperazinyl-2-aminobenzene; 2-Piperazinoaniline; Benzenamine, 2-(1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 2-Piperazin-1-Yl-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.