Description

1-(Trimethylsilyl)-1H-1,2,3-Triazole is a versatile organosilicon-protected triazole derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its role as a stable, silylated precursor for click chemistry and heterocyclic compound construction, enabling efficient and selective reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• As a key synthetic intermediate in the preparation of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Utilized in click chemistry applications, particularly as a protected reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Employed in the synthesis of ligands and catalysts for transition metal catalysis and coordination chemistry.
• Serves as a building block for functional materials, including polymers and dendrimers with tailored properties.
• Used in agrochemical research for the development of novel herbicides, fungicides, and plant growth regulators.
• Acts as a protecting group strategy in multi-step organic synthesis to mask the reactive NH group of 1,2,3-triazole.

Basic Information

Product Name	1-(Trimethylsilyl)-1H-1,2,3-Triazole
CAS No.	13257-88-0
Molecular Formula	C5H11N3Si
Molecular Weight	141.25 g/mol
Synonyms	1-(Trimethylsilyl)-1H-1,2,3-triazole; 1H-1,2,3-Triazole, 1-(trimethylsilyl)-; 1-TMS-1,2,3-triazole; (Trimethylsilyl)triazole; TMS-Triazole; 1-(Trimethylsilyl)triazole; 1,2,3-Triazole, 1-(trimethylsilyl)-; 1-Trimethylsilyl-1H-[1,2,3]triazole
EINECS	Contact for details

Quality Control

Our 1-(Trimethylsilyl)-1H-1,2,3-Triazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.