Description

2-Amino-2-(4-Methylphenyl)Acetic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a phenylalanine-like structure with a para-methyl substituent. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), peptidomimetics, and novel therapeutic agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with enhanced activity.
• Peptide Research & Modification: Used in peptide chemistry to introduce non-natural amino acid residues, altering biological activity and stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Biochemical Research: Tool compound for studying enzyme mechanisms and metabolic pathways involving amino acid analogs.
• Specialty Chemical Production: Intermediate for fine chemicals, dyes, and advanced materials requiring specific aromatic amino acid motifs.

Basic Information

Product Name	2-Amino-2-(4-Methylphenyl)Acetic Acid
CAS No.	13227-01-5
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	4-Methyl-DL-phenylglycine; (4-Methylphenyl)glycine; 2-Amino-2-(p-tolyl)acetic acid; p-Methylphenylglycine; α-Amino-4-methylbenzeneacetic acid; DL-4-Methylphenylglycine; Amino(p-tolyl)acetic acid; 2-Amino-2-(4-tolyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(4-Methylphenyl)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Specified upon request (DL, D, or L)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.