Description

2,3-o-Isopropylidene-D-Ribofuranoside is a key chiral building block and protected ribose derivative essential for nucleoside synthesis. This high-purity intermediate is critical for ensuring the stereochemical integrity and yield of complex pharmaceutical compounds. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing antiviral agents, anticancer drugs, and other nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of antiviral and anticancer nucleoside analogs.
• Nucleoside Chemistry: Serves as a protected D-ribose donor in the stereoselective construction of nucleosides and their modified derivatives.
• Biochemical Research: Used in the study of enzyme mechanisms and as a precursor for labeled compounds in metabolic pathway tracing.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring specific sugar moieties.
• Carbohydrate Chemistry: Acts as a versatile chiral synthon for constructing oligosaccharides and glycoconjugates with defined stereochemistry.
• Process Development: Utilized in scaling up the production of active pharmaceutical ingredients (APIs) that contain ribofuranoside structures.

Basic Information

Product Name	2,3-o-Isopropylidene-D-Ribofuranoside
CAS No.	13199-25-2
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	1,2-O-Isopropylidene-D-ribofuranose; D-Ribose, 1,2-O-(1-methylethylidene)-; 1,2-O-Isopropylidene-α-D-ribofuranose; Isopropylidene-D-ribofuranose; 1,2-O-(1-Methylethylidene)-α-D-ribofuranose; α-D-Ribofuranose, 1,2-O-isopropylidene-; D-(-)-1,2-O-Isopropylideneribofuranose; 2,3-O-Isopropylidene-D-ribose
EINECS	236-167-8

Quality Control

Our 2,3-o-Isopropylidene-D-Ribofuranoside is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-50° to -55° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.