Description

2-Bromo-5-Nitrothiophene is a versatile halogenated nitroheterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and nitro substituents on the thiophene ring, makes it a highly reactive intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antimicrobial and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Material Science: Serves as a monomer or building block for conductive polymers, organic semiconductors, and advanced electronic materials.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce complex functionalities.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Bromo-5-Nitrothiophene
CAS No.	13195-50-1
Molecular Formula	C4H2BrNO2S
Molecular Weight	207.99 g/mol
Synonyms	2-Bromo-5-nitrothiophene; 5-Nitro-2-bromothiophene; Thiophene, 2-bromo-5-nitro-; 2-Bromothiophene-5-nitrile (incorrect but common misnomer); 2-Bromo-5-nitro-thiophene; 2-Br-5-NO2-Thiophene; NSC 403119; 13195-50-1
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Nitrothiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.