Description

Ethyl 4-Bromoacetoacetate is a versatile brominated acetoacetate ester, serving as a crucial synthetic intermediate in organic chemistry. Its value lies in its reactive bromine and carbonyl functionalities, enabling its use in the construction of complex heterocyclic and pharmaceutical compounds. This high-purity building block is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce the 4-bromoacetoacetate moiety into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds and potential kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromoacetyl group is incorporated into bioactive molecules.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and complex organic ligands used in catalysis.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Heterocyclic Chemistry: Employed in the synthesis of pyrroles, pyrazoles, and other nitrogen-containing heterocycles via condensation reactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique properties.

Basic Information

Product Name	Ethyl 4-Bromoacetoacetate
CAS No.	13176-46-0
Molecular Formula	C6H9BrO3
Molecular Weight	209.04 g/mol
Synonyms	4-Bromoacetoacetic Acid Ethyl Ester; Ethyl 4-Bromo-3-oxobutanoate; Ethyl α-Bromoacetoacetate; 3-Oxo-4-bromobutanoic Acid Ethyl Ester; 4-Bromo-3-oxobutanoic Acid Ethyl Ester; Acetoacetic Acid, 4-Bromo-, Ethyl Ester; Bromoacetoacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Bromoacetoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Density	~1.5 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.