Description

4-Nitro-2-Thiophenecarboxylic Acid is a high-purity, functionalized heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and specialty materials, where the nitro and carboxylic acid groups offer versatile sites for further chemical modification. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive functional groups.
• Material Science Research: Serves as a monomer or precursor for conducting polymers, organic semiconductors, and advanced polymeric materials with specific electronic properties.
• Organic Synthesis & Catalysis: Employed as a versatile substrate in metal-catalyzed cross-coupling reactions and for the preparation of complex ligand systems.
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and pigments, especially thiophene-based colorants.

Basic Information

Product Name	4-Nitro-2-Thiophenecarboxylic Acid
CAS No.	13138-70-0
Molecular Formula	C5H3NO4S
Molecular Weight	173.15 g/mol
Synonyms	2-Carboxy-4-nitrothiophene; 4-Nitrothiophene-2-carboxylic Acid; 4-Nitro-2-thiophenecarboxylic acid; 4-Nitrothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-nitro-; 4-Nitro-2-thiophene carboxylic acid; 4-Nitrothiophene-2-carboxylate; 4-Nitro-2-thiophenecarboxylate
EINECS	236-099-5

Quality Control

Our 4-Nitro-2-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is moisture-sensitive; ensure the container is kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.