Description

Tetrahydro-2H-thiopyran-4-carboxylic acid-1-oxide is a versatile, high-purity heterocyclic building block and chiral intermediate of significant importance in advanced organic synthesis. Its core value lies in its functionalized thiopyran oxide scaffold, which is crucial for constructing complex molecules with specific stereochemistry and biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides due to its bioactive heterocyclic structure.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the development of novel polymers and organic electronic materials with tailored properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	Tetrahydro-2H-thiopyran-4-carboxylic acid-1-oxide
CAS No.	13129-22-1
Molecular Formula	C6H10O3S
Molecular Weight	162.21 g/mol
Synonyms	4-Carboxytetrahydro-2H-thiopyran 1-oxide; Tetrahydro-2H-thiopyran-4-carboxylic acid S-oxide; 1-Oxidotetrahydro-2H-thiopyran-4-carboxylic acid; 4-Thiane carboxylic acid 1-oxide; Thiomorpholine-3-carboxylic acid 1,1-dioxide (related); Tetrahydrothiopyran-4-carboxylic acid 1-oxide; 1,1-Dioxo-1λ⁶-thiomorpholine-3-carboxylic acid (tautomer/form).
EINECS	Contact for details

Quality Control

Our Tetrahydro-2H-thiopyran-4-carboxylic acid-1-oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.