Description

Hexahydro-1-(Hydroxymethyl)-2H-Azepin-2-One is a versatile seven-membered lactam derivative, also known as 7-Hydroxymethylcaprolactam. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring a hydroxymethyl functional group on a saturated azepinone ring, makes it highly valuable for the production of pharmaceuticals, agrochemicals, and high-performance polymers. Key industries that utilize this intermediate include pharmaceutical R&D, fine chemical manufacturing, and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its ring structure contributes to biological activity.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent for specialty polyamides (nylons) and coatings, enhancing thermal and mechanical properties.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex nitrogen-containing heterocycles and macrocycles.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Cosmetic & Personal Care Ingredients: Functions as an intermediate for synthesizing conditioning agents and film-forming polymers in high-end formulations.

Basic Information

Product Name	Hexahydro-1-(Hydroxymethyl)-2H-Azepin-2-One
CAS No.	13088-64-7
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	7-Hydroxymethylcaprolactam; 1-(Hydroxymethyl)azepan-2-one; 1-(Hydroxymethyl)hexahydro-2H-azepin-2-one; 7-Hydroxymethyl-ε-caprolactam; (Hexahydro-2-oxo-1H-azepin-1-yl)methanol; 1H-Azepin-2-one, hexahydro-1-(hydroxymethyl)-; Caprolactam, 7-hydroxymethyl-
EINECS	Contact for details

Quality Control

Our Hexahydro-1-(Hydroxymethyl)-2H-Azepin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in the pharmaceutical and fine chemical sectors. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the atmosphere. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.