Description

3-Chloro-2-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and a nitrile group ortho to a chlorine substituent, makes it a valuable building block for constructing complex molecules with tailored properties. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzophenone or benzamide core structure.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, leveraging the reactivity of the chloro and cyano groups for heterocycle formation.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and coordination chemistry due to its potential chelating sites.
• Material Science Research: Intermediate in the creation of advanced polymers, liquid crystals, or organic electronic materials where specific aromatic substitution patterns are required.
• Dye and Pigment Chemistry: Serves as a starting material for synthesizing complex colorants and functional dyes.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in bespoke, multi-step synthetic routes for client-specific targets.

Basic Information

Product Name	3-Chloro-2-Hydroxybenzonitrile
CAS No.	13073-27-3
Molecular Formula	C7H4ClNO
Molecular Weight	153.56 g/mol
Synonyms	2-Hydroxy-3-chlorobenzonitrile; 3-Chloro-2-cyanophenol; 3-Chlorosalicylonitrile; 2-Cyano-6-chlorophenol; 3-Chloro-2-hydroxybenzenecarbonitrile; Benzonitrile, 3-chloro-2-hydroxy-; 6-Chloro-2-hydroxybenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Hydroxybenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and production processes. Our standard quality commitment includes rigorous testing for identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing lot-specific results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.