Description

(S)-4-Chloro-1,2-Epoxybutane is a high-value chiral epoxide building block, essential for the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. Its defined stereochemistry provides a critical advantage in creating active pharmaceutical ingredients (APIs) with high optical purity, directly impacting efficacy and safety profiles. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel chiral molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-blockers, antiviral agents, and other enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Building Block: Serves as a versatile precursor in asymmetric synthesis for creating complex natural products and specialty chemicals.
• Polymer Modification: Employed in the synthesis of chiral polymers and resins with specialized optical or mechanical properties.
• Ligand and Catalyst Development: Acts as a starting material for preparing chiral ligands used in asymmetric catalysis.
• Academic and R&D: Utilized in research laboratories for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(S)-4-Chloro-1,2-Epoxybutane
CAS No.	13067-79-3
Molecular Formula	C4H7ClO
Molecular Weight	106.55 g/mol
Synonyms	(S)-(-)-Epichlorohydrin; (S)-(-)-1-Chloro-2,3-epoxypropane; (S)-(-)-3-Chloro-1,2-epoxypropane; (S)-Epichlorohydrin; (S)-1-Chloro-2,3-epoxypropane; (2S)-2-(Chloromethyl)oxirane; (S)-ECH; (S)-4-Chloro-1,2-epoxybutane (Note: Common synonyms often refer to the 3-carbon analog; the 4-carbon butane derivative is specified).
EINECS	Contact for details

Quality Control

Our (S)-4-Chloro-1,2-Epoxybutane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure compliance with stringent specifications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for extended stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.