Description

Glycine 1-Methylethyl Ester is a versatile organic ester derivative of the amino acid glycine, widely utilized as a key building block in organic synthesis. Its primary value lies in its role as a protected glycine equivalent, enabling the controlled introduction of the glycine moiety into more complex molecules under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of peptides, active pharmaceutical ingredients (APIs), and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of peptide-based drugs, prodrugs, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and plant growth regulators that incorporate amino acid backbones.
• Peptide Chemistry: Serves as a protected glycine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Fine Chemical Production: Employed in the manufacture of complex organic molecules, including dyes, flavors, and fragrances.
• Bioconjugation & Linker Chemistry: Useful for creating ester-based linkers in bioconjugation strategies for drug delivery systems.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies.

Basic Information

Product Name	Glycine 1-Methylethyl Ester
CAS No.	13048-66-3
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	Glycine Isopropyl Ester; Isopropyl Glycinate; 2-Aminoacetic Acid 1-Methylethyl Ester; 2-Aminoacetic Acid Isopropyl Ester; Isopropyl 2-Aminoacetate; Glycine, Isopropyl Ester; Aminoacetic Acid Isopropyl Ester
EINECS	235-930-7

Quality Control

Our Glycine 1-Methylethyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, which include results from tests such as assay (HPLC), identification (IR, NMR), and impurity profiling. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.