Description

(4S)-2,2-Dimethyl-5β-[(4R)-2,2-Dimethyl-1,3-Dioxolane-4β-Yl]-1,3-Dioxolane-4α-Carbaldehyde is a high-purity, chiral protected aldehyde derivative, serving as a critical advanced intermediate in sophisticated organic synthesis. Its precise stereochemistry and functional group protection make it invaluable for constructing complex molecular architectures with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), nucleosides, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Nucleoside & Nucleotide Chemistry: Used in the preparation of modified nucleosides and nucleotides for antiviral and anticancer research.
• Asymmetric Synthesis: Employed as a chiral precursor in catalytic asymmetric reactions to introduce stereocenters.
• Carbohydrate & Sugar Chemistry: Serves as a protected aldehyde synthon for the construction of complex sugar derivatives and glycomimetics.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical control.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(4S)-2,2-Dimethyl-5β-[(4R)-2,2-Dimethyl-1,3-Dioxolane-4β-Yl]-1,3-Dioxolane-4α-Carbaldehyde
CAS No.	13039-93-5
Molecular Formula	C12H20O5
Molecular Weight	244.28 g/mol
Synonyms	(4S)-2,2-Dimethyl-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,3-dioxolane-4-carbaldehyde; (4S)-2,2-Dimethyl-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,3-dioxolane-4-carboxaldehyde; (4S)-5-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde; D-Glyceraldehyde Acetonide Dimer; D-Glyceraldehyde Diacetonide; (4S,4'R)-2,2,2',2'-Tetramethyl-4,4'-bi(1,3-dioxolane)-4-carbaldehyde; Chiral Protected Glyceraldehyde Derivative
EINECS	Contact for details

Quality Control

Our (4S)-2,2-Dimethyl-5β-[(4R)-2,2-Dimethyl-1,3-Dioxolane-4β-Yl]-1,3-Dioxolane-4α-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.