Description

3,3-Diethyl-3H-Diazirine is a highly versatile and reactive diazirine compound, valued for its role as a photoactivatable crosslinking agent. Its core value proposition lies in its ability to generate highly reactive carbene intermediates upon photolysis with UV or visible light, enabling the formation of covalent bonds with proximal molecules. This makes it an essential tool for researchers and manufacturers in pharmaceutical development, proteomics, and materials science, particularly for studying biomolecular interactions and creating advanced polymer networks.

Application

• Photoaffinity Labeling (PAL): A critical reagent for mapping drug-protein interactions and identifying biological targets by forming irreversible crosslinks upon light activation.
• Proteomics and Crosslinking Mass Spectrometry (XL-MS): Used to "freeze" and analyze protein-protein interactions, protein complexes, and structural conformations in their native state.
• Polymer and Surface Modification: Serves as a photo-crosslinker for the synthesis and functionalization of polymers, hydrogels, and material surfaces to introduce specific chemical properties.
• Bioconjugation: Enables the site-specific labeling of biomolecules (e.g., antibodies, peptides) with tags, dyes, or other functional groups for imaging and diagnostic applications.
• Chemical Biology Probes: Incorporated into small molecule probes to investigate metabolic pathways and enzyme mechanisms through light-induced trapping.
• Materials Science Research: Utilized in the development of photo-patternable materials and for studying interfacial chemistry in composite materials.

Basic Information

Product Name	3,3-Diethyl-3H-Diazirine
CAS No.	13036-61-8
Molecular Formula	C6H12N2
Molecular Weight	112.18 g/mol
Synonyms	Diethyldiaziridine; 3,3-Diethyl-3H-diazirine; 3,3-Diethyl-diaziridine; Diaziridine, 3,3-diethyl-; 3H-Diazirine, 3,3-diethyl-; Diethyl diaziridine; 3,3-Diethyldiaziridine
EINECS	Contact for details

Quality Control

Our 3,3-Diethyl-3H-Diazirine is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its highly volatile nature, ensure containers are kept tightly sealed at all times and stored at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.