Description

N-Phenyl-4-Trimethylsilylaniline is a specialized organosilicon compound featuring both an aromatic amine and a trimethylsilyl protecting group. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for the development of functional materials and pharmaceuticals. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those requiring silyl-protected amine functionalities.
• Material Science: Used in the development of organic semiconductors, liquid crystals, and advanced polymers where its structure can influence electronic properties and stability.
• Agrochemical Research: Acts as a building block for creating new active ingredients with modified biological activity and environmental persistence.
• Cross-Coupling Reactions: Functions as a reagent in palladium-catalyzed reactions, such as Buchwald-Hartwig amination, for constructing complex nitrogen-containing aromatic systems.
• Protecting Group Chemistry: The trimethylsilyl group can be used to protect the aniline nitrogen during multi-step synthetic sequences, offering selective deprotection pathways.

Basic Information

Product Name	N-Phenyl-4-Trimethylsilylaniline
CAS No.	13024-18-5
Molecular Formula	C15H19NSi
Molecular Weight	241.40 g/mol
Synonyms	4-(Trimethylsilyl)aniline, N-Phenyl; 4-(Trimethylsilyl)diphenylamine; N-Phenyl-4-(trimethylsilyl)benzenamine; 4-Anilinophenyltrimethylsilane; Benzenamine, 4-(trimethylsilyl)-N-phenyl-; p-(Trimethylsilyl)diphenylamine
EINECS	Contact for details

Quality Control

Our production of N-Phenyl-4-Trimethylsilylaniline adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.