Description

1-(Chloromethyl)-4-Ethynylbenzene is a versatile bifunctional aromatic building block featuring both a reactive chloromethyl group and an ethynyl moiety. This compound matters for its unique ability to serve as a key intermediate in the synthesis of complex molecules, enabling carbon-carbon bond formation and polymer functionalization. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients, ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of biologically active molecules and potential drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty resins, conductive polymers, and advanced composites.
• Ligand & Catalyst Preparation: Utilized in the synthesis of complex ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Organic Synthesis Building Block: Enables Sonogashira coupling and other palladium-catalyzed reactions to create extended π-conjugated systems.
• Life Sciences Research: Employed in chemical biology for probe and tag synthesis due to its click chemistry compatibility via the alkyne group.

Basic Information

Product Name	1-(Chloromethyl)-4-Ethynylbenzene
CAS No.	10601-98-6
Molecular Formula	C9H7Cl
Molecular Weight	150.60 g/mol
Synonyms	4-Ethynylbenzyl Chloride; p-Ethynylbenzyl Chloride; (4-Ethynylphenyl)methyl Chloride; 1-Chloromethyl-4-ethynylbenzene; 4-(Chloromethyl)phenylacetylene; 10601-98-6; p-(Chloromethyl)phenylacetylene
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-4-Ethynylbenzene is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to the light-sensitive nature and reactive functional groups, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.