Description

3-Methylenecyclobutylmethyl Bromide is a versatile and reactive organobromine compound, serving as a crucial alkylating agent and building block in advanced organic synthesis. Its unique strained cyclobutyl structure with an exocyclic methylene group makes it a valuable intermediate for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactive bromide facilitates the introduction of the methylenecyclobutyl moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands or organometallic catalysts used in asymmetric synthesis.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for developing polymers with unique thermal and mechanical properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction methodologies and synthesizing complex natural product analogs.
• Fine Chemical Production: Intermediate in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	3-Methylenecyclobutylmethyl Bromide
CAS No.	10555-46-1
Molecular Formula	C6H9Br
Molecular Weight	161.04 g/mol
Synonyms	(3-Methylenecyclobutyl)methyl Bromide; Bromomethyl-3-methylenecyclobutane; 3-(Bromomethyl)methylenecyclobutane; 3-Methylenecyclobutanemethyl Bromide; Cyclobutane, 1-(bromomethyl)-3-methylene-; 1-(Bromomethyl)-3-methylenecyclobutane
EINECS	Contact for details

Quality Control

Our 3-Methylenecyclobutylmethyl Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Assay (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.